“I have been on omeprazole for six years. My GP never once mentioned B12. The brain fog had been getting worse for two years and I had just accepted it. Six weeks on this and I feel sharper than I have in years. My husband said I seemed like myself again.”
Taking Omeprazole or Lansoprazole? This Is Why Your Brain Fog Keeps Coming Back.
The medication managing your acid reflux is clinically documented to deplete the one nutrient your brain depends on most, and most people are never told.
- Restores the B12 your acid reflux medication has been quietly depleting
- Clears the slow thinking and word-finding difficulties that sleep cannot fix
- Uses active forms that bypass the stomach acid your medication suppresses
- Works even if you have tried B vitamins before and felt nothing
- No conversion required. Reaches your brain the moment it is absorbed.
- All eight B vitamins in their active, pre-converted forms
MBG
Most B complex supplements use a synthetic form of B12 called cyanocobalamin. Before your body can use it, it has to be converted into the active form your brain can actually work with. That conversion relies on stomach acid and specific digestive enzymes. Proton pump inhibitors like omeprazole and lansoprazole suppress stomach acid, which is exactly what they are designed to do. This means that for anyone on a PPI, standard B12 supplements may be delivering almost nothing to the brain, because the conversion mechanism has been suppressed by the medication itself. The Vitamin B Complex by rynw uses methylcobalamin, the active form of B12 that requires no conversion and no stomach acid. Your body can use it the moment it is absorbed, regardless of your medication.
Most people notice the first changes within two to three weeks. The most common early signs are slightly clearer thinking in the mornings and less reliance on caffeine to get through the afternoon. By weeks four to six, the word-finding gaps that have become normal start to become less frequent. By month two to three, the change is usually consistent and significant enough that people around you notice before you mention it. The key is consistency. One capsule every morning. The benefits compound with daily use.
Yes. The Vitamin B Complex by rynw contains only active-form B vitamins and is safe to take alongside your acid reflux medication. You do not need to stop your PPI to take this. In fact, the formula is specifically designed to work regardless of your stomach acid levels because the active forms it contains do not rely on the conversion process that PPIs interfere with. If you are on any other prescription medication, we always recommend checking with your GP before starting any new supplement.
The form determines whether the vitamin actually reaches your brain. The B12 in 95% of supplements, including most multivitamins, is cyanocobalamin, a synthetic form your body has to convert before it can use it. That conversion depends on stomach acid and specific enzymes that decline with age and are directly suppressed by PPI medication. Methylcobalamin, the form used in this formula, is already in the active state your nervous system can use directly. No conversion. No stomach acid required. No delay. The difference between the two is not a marketing claim. It is the entire difference between a supplement that works and one that does not.
One capsule every morning with food and a glass of water. Morning use is recommended because B vitamins support energy metabolism and taking them earlier in the day works with your body’s natural rhythms. Consistency matters more than timing. The benefits build with daily use over weeks and months.
Yes. The capsule shell is plant-derived hypromellose. The formula contains no animal products, no gelatin, no dairy, no gluten and no artificial additives. It is fully vegan and non-GMO certified.
Based on What You Just Told Us
You have been experiencing these symptoms for a significant period of time. You have tried supplements that have not made a meaningful difference. And you are currently taking a medication that is clinically documented to deplete the specific nutrient your brain depends on most.
Here is exactly what is happening inside your body, and why The Vitamin B Complex by rynw is specifically designed to address it.
The symptoms you described, slow thinking, words going missing, waking up tired, walking into rooms and standing blank, are not random signs of ageing. They are what B vitamin deficiency looks like. And your medication has a clinically documented role in creating that deficiency. What follows explains the mechanism clearly and tells you exactly what is different about this formula.
SKIP TO THE PRODUCT →What the Research Shows
Peer-reviewed clinical evidence behind the formula
Adults who took an active B vitamin complex for 28 days lasted 26% longer before exhaustion, with measurable drops in the fatigue chemicals that build up in the blood during physical and mental exertion. Less crash. More capacity. Every day.
In a direct head-to-head comparison, 73% of people taking methylcobalamin, the active form of B12 in this formula, saw significant improvements in nerve pain, numbness and lost sensation. The group taking standard B12 saw less than half that result.
Adults who took active B vitamins daily for two years showed significant improvements across memory, executive function and overall mental sharpness, with family members noticing the difference before the participants mentioned it.
The Oxford University VITACOG trial found that active B vitamin supplementation reduced the rate of brain tissue atrophy by 30% compared to placebo. In participants with elevated homocysteine, a marker strongly associated with cognitive decline, the protection was 53%.
Here’s What No One Tells You About Your Acid Reflux Medication and Your Brain
Millions of people in the UK take omeprazole, lansoprazole or pantoprazole every day. It manages the acid reflux. It does its job. But there is a side effect almost nobody mentions at the point of prescription.
PPIs work by suppressing stomach acid production. That is their entire function and they do it well. But stomach acid plays a second role that most patients are never told about. It is the mechanism your body uses to release and absorb vitamin B12, from everything you eat and everything you take.
Research published in Neurology found that long-term PPI use was associated with significantly lower B12 levels. Research from JAMA found that two or more years of PPI use was linked to a 65% increased risk of B12 deficiency. The longer you take them, the greater the depletion.
B12 is not optional for your brain. It is the nutrient your brain uses to maintain the myelin sheath, the protective coating around every nerve fibre that carries your thoughts. When B12 is depleted, the signals slow. Words take longer to arrive. Thoughts slip. The room you walked into no longer holds its reason.
Researchers now believe subclinical B vitamin deficiency, low enough to cause real symptoms but not low enough to show up clearly on a standard blood test, is far more widespread than previously thought. You can be taking your medication, doing everything right, and still be running low.
The problem is not whether you are taking B vitamins. It is whether the form you are taking can survive the journey to your brain.
- Slow thinking or mental heaviness that was not there before
- Words going missing mid-sentence
- Walking into rooms and standing there completely blank
- Waking up tired regardless of how much sleep you get
- Low mood or a shorter fuse than you used to have
- Tingling or numbness in your hands or feet
- PPI medication suppressing the stomach acid needed to absorb B12
- Age-related decline in stomach acid and digestive enzymes compounding the problem
- Supplements using inactive forms that require the same acid-dependent conversion the medication is blocking
- Standard blood tests missing the deficiency because the NHS threshold may be set too low
Every B Vitamin. Every Active Form. One Complete Formula.
Most B complex supplements include all eight vitamins on the label, but use inactive forms your body has to convert before it can use them. For anyone on a PPI, that conversion is blocked. Every vitamin in this formula is already in its active, ready-to-use state.
This is the most important vitamin in the formula for anyone on a proton pump inhibitor. Standard B12 supplements use cyanocobalamin, a synthetic inactive form that requires conversion by stomach acid and digestive enzymes. PPIs suppress stomach acid, which means for anyone on long-term acid reflux medication, standard B12 supplements may be delivering almost nothing to the brain. Methylcobalamin is already in the active form your nervous system uses directly. No conversion. No stomach acid required. No medication interaction. The moment it is absorbed it is available to your brain.
B1 is the vitamin your body uses to convert the food you eat into energy your brain and cells can actually use. Without adequate B1, that conversion breaks down, leaving you tired, foggy and running on empty regardless of how much you eat or sleep. Clinical trials have shown significant reductions in chronic fatigue with meaningful B1 supplementation. Most B complexes include B1 at token doses that make no real difference. This formula contains 100mg, a clinically meaningful amount.
Every cell in your body needs B2 to produce energy. But B2 has a second critical function: it activates B6 and folate so they can do their jobs. Without enough B2, neither of the nutrients responsible for mood, focus and neurotransmitter production can function correctly. B2 is the quiet foundation the rest of the formula depends on. Without it, even the right forms of the other vitamins cannot work properly.
B3 in its niacinamide form fuels the NAD+ metabolic pathways that power sustained brain energy throughout the day. Without adequate B3, the brain’s energy supply becomes uneven, creating the mid-morning fog and afternoon crash that no amount of coffee can reliably fix. Niacinamide is the non-flushing form of B3, meaning it delivers the full cognitive and energy benefit without the skin flushing associated with other forms of niacin.
B5 is the vitamin your body burns through fastest under stress. It is directly involved in the synthesis of coenzyme A, the compound your cells use to convert fats, proteins and carbohydrates into usable energy. It also supports the adrenal system that governs your stress response. When B5 is depleted, energy conversion slows and stress fatigue accumulates faster. Modern life burns through B5 at a rate that diet alone struggles to replace.
B6 in its active P5P form is required for the synthesis of serotonin, dopamine and GABA, the neurotransmitters that govern mood, focus and your sense of calm. Most supplements use the inactive form pyridoxine, which requires conversion before the brain can use it. P5P is already in the active state. Your brain can use it the moment it is absorbed. No conversion. No delay. The difference is felt in mood stability, mental clarity and the ability to stay calm under pressure.
B7 supports the metabolic pathways that allow your body to extract energy from fats and proteins. It works quietly in the background, maintaining the efficiency of the energy processes that the more prominent B vitamins depend on. Biotin also supports healthy nervous system function and plays a role in gene expression. At 300mcg this formula provides a meaningful and functional dose rather than the token inclusion found in most B complexes.
The folate in most supplements is called folic acid. Before your body can use it, folic acid must be converted into its active form, 5-MTHF. This formula uses 5-MTHF directly, already in the active state. This matters especially for the estimated 40% of people who carry a genetic variant that impairs folic acid conversion. With 5-MTHF, conversion is not required. The active form is available to your cells immediately.
What Sets The Vitamin B Complex by rynw Apart
Especially if you take acid reflux medication. Most B complex supplements look the same on paper. But there are critical differences that determine whether what you are taking actually works inside your body.
Most B complexes use the cheap synthetic forms of B12, folate and B6, forms your body has to convert before it can use them. That conversion relies on stomach acid and enzymes that decline with age and are directly suppressed by PPI medication. Many people taking these supplements are absorbing almost nothing. Every vitamin in this formula is already in its active, ready-to-use form. What is on the label is what your cells actually receive, regardless of your stomach acid levels.
This is the only B complex formulated with the PPI absorption barrier specifically in mind. By using active forms throughout, the formula bypasses the conversion steps that PPIs block. You do not need to stop your medication. You do not need to change anything about how you take it. This works alongside it.
Most B complex supplements include every vitamin on the label at doses so small they make no real difference. Every B vitamin in this formula is dosed at a level that reflects what published clinical research actually used. Not a sprinkle. Not a fraction. A real, working dose.
B vitamins do not work in isolation. B12 requires folate. B6 requires B2. NAD+ production requires B3. Selling you one or two B vitamins and calling it a complex leaves entire metabolic pathways unsupported. This formula provides all eight, because anything less is incomplete by design.
No proprietary blends. No vague B complex blend hiding quantities you cannot verify. Every ingredient listed. Every dose disclosed. No gluten, dairy, soy, GMOs or artificial additives. The capsule shell is plant-derived. What you see is exactly what you get.
What Customers on Acid Reflux Medication Are Saying
Verified reviews from customers who made the switch after years of brain fog, slow thinking and word-finding difficulties
“I have been on omeprazole for six years. My GP never mentioned B12. The fog had been getting worse for two years and I just accepted it. Six weeks on The Vitamin B Complex by rynw and I feel sharper than I have in years. My husband said I seemed like myself again.”
“I am 67 and I had started to think the brain fog was just something I had to accept. I was wrong. My word recall is sharper, I feel more present in conversations, and I am not writing everything down anymore because I actually remember things. My daughter noticed before I mentioned it to her.”
“I was sceptical. I have tried B12 supplements before with no effect. Four weeks in and I feel like my brain is working properly again. The word-finding gaps that were driving me mad are happening far less often. My husband noticed before I said anything.”
Simple. One Capsule. Every Morning.
Hassle-free and designed to fit into your existing routine, including alongside your existing medication.
- 1Take 1 capsule daily
- 2Best results with food
- 3Morning use is recommended
- 4Use consistently for 4 to 8 weeks for full effect
Why B Vitamins Are Not Optional If You Take Acid Reflux Medication
Why Choose rynw?
| Feature | ❌ Standard B Complex | ✓ rynw B Complex |
|---|---|---|
| B12 Form | Cyanocobalamin (inactive, requires conversion) | Methylcobalamin (active, no conversion needed) |
| Works with PPI medication | No, conversion is blocked by PPIs | Yes, active forms bypass the PPI barrier |
| Folate form | Folic acid (blocked in 40% of people) | 5-MTHF (active, works for everyone) |
| B6 form | Pyridoxine (inactive) | P5P (active, immediate use) |
| B1 dose | Token amount (often under 5mg) | 100mg clinical dose |
| All 8 B vitamins | Often incomplete or underdosed | All 8 at functional clinical doses |
| Transparency | Proprietary blends, hidden quantities | Every ingredient and dose disclosed |
| Suitable for vegans | Often contains gelatin capsules | Fully vegan, plant-derived capsule |
| Money-back guarantee | Rarely offered | 30-day full refund, no questions asked |
The Vitamin B Complex by rynw
- 1 Month Supply delivered monthly
- 20% off for life, Subscribe & Save
- Clinically dosed, active forms only
- Free UK Shipping
- 30-Day Money-Back Guarantee
- Free UK delivery on every order
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- Cancel, skip, or pause your subscription anytime
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30-Day Results or Full Refund Guarantee
Try The Vitamin B Complex by rynw completely risk-free for 30 days. If you do not feel a meaningful difference in your energy, your mental clarity or your ability to think and hold a thought, contact us and we will refund you in full.
No questions asked. No awkward process. The risk is entirely ours, not yours.
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CLAIM YOUR DISCOUNT TODAY →These statements have not been evaluated by the Food Standards Agency. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. The testimonials featured on this page are from real customers and reflect their personal experiences. Results are not guaranteed. Always consult your GP or healthcare provider before starting any new supplement, particularly if you are taking prescription medications or managing a health condition.